Acta Neurol Scand 1995 Dec;92(6):486-90


Vibrameter testing facilitates the diagnosis of uremic and alcoholic



Hilz MJ, Zimmermann P, Rosl G, Scheidler W, Braun J, Stemper B, Neundorfer B.


Department of Neurology, New York University Medical Center, NY 10016, USA.


The diagnostic sensitivity of Vibrameter and tuning fork examination towards

uremic and alcoholic neuropathy was tested in 75 patients. In 40 uremic and 35

alcoholic patients, we compared the sensitivity of neurological examination,

nerve conduction studies (NCS) and vibration thresholds assessed at the malleoli

by means of Vibrameter and scaled tuning fork. Vibrameter results were

correlated with NCS. Polyneuropathy was diagnosed in 52 patients, but in 16

patients diagnosis depended upon inclusion of Vibrameter testing in the

examination protocol. In uremic patients, Vibrameter (47.5%) showed

abnormalities as often as NCS (45%), and more often than clinical (32.5%) or

tuning fork examination (2.5%). In alcoholic patients, Vibrameter revealed

abnormalities more often (60%) than NCS (34.3%) or tuning fork (14.3%).

Correlations between NCS and vibratory thresholds were low (-0.52 < or = Rs < or

= -0.35). Vibrameter studies are far more sensitive than tuning fork tests. The

technique complements NCS and refines the diagnosis of uremic and alcoholic